Alcohol Researcher Interest Group at LSHTM
This group is open to anyone with an interest in research involving alcohol. The aim of the group is to bring together researchers with an interest in alcohol to develop collaboration and share expertise. This is a joint initiative between the Centre for Global NCDs, Centre for Global Mental Health and ECOHOST – The Centre for Health and Social Change present.
This group had its first meeting in April 2016. We plan to meet a few times a year to discuss relevant topics in Alcohol research suggested by the group. The most recent meeting (September 2016) was on the theme of measurement of alcohol use. This meeting led to interest in developing a “tool kit” for measuring alcohol use in setting where conventional questions on quantity and frequency of consumption are not valid.
Topics for upcoming meetings include Alcohol Policy Research and Alcohol and Mental Health (dates to be confirmed)
Anyone interested in joining this group should contact Sarah Cook firstname.lastname@example.org.
Ideas and suggestions for developing this group are welcome.
Cardiovascular Disease in Russia
Description: Russia has the highest mortality from cardiovascular disease in the world. This project aims to identify key reasons for this very high public health burden which will help inform the development of strategies to improve the situation. A series of detailed studies compares the cardiovascular system of a large sample of the Russian population with that in Norway and other Western countries. It brings together for the first time available high quality data from epidemiological studies in Russia to generate the most authoritative summary of cardiovascular risk factors levels in Russia. Comparative studies of the validity of cause of death in Russia and Norway are also conducted as well as a systematic investigation of the potential contribution of access to and standards of treatment.
Diabetes Management in DRC
Description: This study is carried out in partnership with the Manson Unit of Médecins Sans Frontières (MSF) and will take place in the MSF programme in Mweso, North Kivu in the Democratic Republic of the Congo (DRC). The aim of the study is to assess the feasibility and effectiveness of an intervention to implement treatment and management for diabetes in Mweso. The study objectives are to: measure the effectiveness of care on outcomes for patients with diabetes; assess the baseline prevalence of diabetes and diabetes risk-factors; measure the economic feasibility of implementing care for insulin dependent diabetes; and explore perspectives of health workers and patients on compliance patterns for care for insulin dependent diabetes. Research methods include a cohort of diabetes patients, cross-sectional household surveys, and qualitative research.
PURE Critical Barriers
Description: The goal of this project is to understand inequalities in accessing and continuing effective care for cardiovascular diseases in low-, middle- and high income countries. The objectives of the study are to assess the scale and nature of inequalities in influencing the use of evidence-based CVD prevention measures and treatments for cardiovascular disease (hypertension, stable angina, acute myocardial infarction, heart failure, stroke), and identify the socio-demographic, economic, and community determinants of variation within countries. Research methods include statistical analysis of data from the PURE data.
Description: This project seeks to improve the management of hypertension, a condition that afflicts around a billion people worldwide, nearly three-quarters of whom live in developing countries. The project has several phases: a systematic review of barriers to optimal hypertension management, analysis of those barriers in Colombia and Malaysia, development of a complex intervention including new simplified guidelines for detection and treatment, task shifting, and fixed dose combination therapy (the polypill).
Collaborators: Population Health Research Institute
Khatib R, Schwalm J-D, Yusuf S, Haynes BR, McKee M, Khan M, Nieuwlaat R. Patient and healthcare provider barriers to hypertension awareness, treatment and follow up: A systematic review of qualitative and quantitative studies. PLOS One 2014; 9(1): e84238. doi:10.1371/journal.pone.0084238
Maimaris W, Paty J, Perel P, Legido-Quigley H, Balabanova D, Nieuwlaat R, McKee M. The influence of health systems on hypertension awareness, treatment and control: a systematic literature review. PLOS Med 2013: 10(7): e1001490. doi:10.1371/journal.pmed.1001490
Media: HOPE-4 Video
For further information, please visit: http://www.gacd.org/projects/current-projects/hypertension/project-pages/project2
The CONCORD Programme – Global Surveillance of Cancer Survival
The CONCORD programme for global surveillance of cancer survival is led by the Cancer Survival Group at the London School of Hygiene & Tropical Medicine. The most recent study examined data for over 25 million individual cancer patients diagnosed 1995-2009, provided by 279 population-based cancer registries in 67 countries that are home to two-thirds of the world’s population.
Dr Claudia Allemani was awarded the UK Faculty of Public Health’s inaugural Global Public Health Award in 2016 for her work on the CONCORD programme.
The CONCORD programme is endorsed by 31 national and international agencies, including the Organisation for Economic Co-operation and Development (OECD), the National Cancer Institutes of France and the USA, the US Centers for Disease Control and Prevention, and the World Bank. For more information please see our website.
Community-based Hypertension Improvement Program (ComHIP)
The Centre for Global NCD of the LSHTM is leading the evaluation and cost-effective analysis of a community-based hypertension program (ComHIP) in a district in Ghana as an important contribution to the development of evidence-based innovative approaches to the management of non-communicable diseases in low & middle income countries.
ComHIP is a community based-program that engages both the public and private sectors in the community to improve the management and control of hypertension in the Lower Manya Krobo district. It aims to enhance the capacity of the Ghana Health Service through task shifting and innovative technology solutions to improve access to quality and affordable services for hypertension and other cardiovascular diseases (CVDs). The project also aims to improve the capacity of patients in managing their own conditions and risk factors.
For this project LSHTM is partnering with the Ghana Health Service, FHI360, School of Public Health of the University of Ghana and the Novartis Foundation.
Using computerised clinical data to investigate the links between long-term drug treatments and cancer risk
There are concerns that some widely-used drug treatments might be linked to an increase in the risk of cancer. The aim of the project is to investigate such concerns making use of routinely collected data on large numbers of patients observed over a number of years, recorded in electronic healthcare databases.
The course and outcome of alcohol use disorders (AUD): A population based cohort study in Goa, India
Exploring early and life-course determinants of chronic kidney disease
Epidemiology of infections amongst people with chronic kidney disease and diabetes
Using routine health records, this project investigates whether people with diabetes who also have chronic kidney disease are at a higher risk of infections than those without kidney disease, and whether people with kidney disease receive vaccinations for vaccine-preventable diseases.
Nutritional challenges, abdominal adiposity and type 2 diabetes in Indians
Lead: Hannah Kuper
This study was undertaken in Hyderabad, India, to assess the impact of early life nutritional supplementation and later life rural-urban migration on diabetes and other chronic diseases.
Improving the assessment and treatment of childhood obesity
As part of the PROMISE Programme, two projects based at LSHTM aim to:
1. Scope the impact of the National Child Measurement Programme feedback on the child obesity pathway; and 2. Develop a new electronic tool to improve childhood obesity management in primary care.
REPAIR and ERICCA trials
Lead: Tim Clayton
The REPAIR trial aims (Renal protection against ischaemia reperfusion injury in transplantation) to determine if remote ischaemic preconditioning (RIPC) improves renal function after transplantation. The ERICCA trial (Effect of Remote Ischaemic preConditioning on clinical outcomes in patients undergoing Coronary Artery Bypass Graft surgery) aims to determine whether remote ischaemic preconditioning (RIC) improves clinical outcomes after cardiac surgery.
Leverhulme centre for integrative research on agriculture and health
The determinants of international and socio-economic variations in female breast cancer survival
Lead: Laura Woods
This research examines the determinants of low survival amongst women with breast cancer in England in comparison to Australia, and in poorer women in comparison to richer women in the United Kingdom.
Timely diagnosis and inequalities in breast cancer survival
Lead: Laura Woods
The purpose of this research is to provide robust, quantitative evidence of the effectiveness of mammographic screening for reducing inequalities in survival between women of different socio-economic groups and of different ethnicities.